The domain within your query sequence starts at position 98 and ends at position 168; the E-value for the XPGI domain shown below is 1.4e-33.



Xeroderma pigmentosum G I-region
SMART accession number:SM00484
Description: domain in nucleases
Interpro abstract (IPR006086):

This entry represents a domain found on Xeroderma Pigmentosum Complementation Group G (XPG) protein [ (PUBMED:8206890) ]. XPG is a DNA endonuclease involved in DNA excision repair [ (PUBMED:8078765) ]. The internal XPG (XPG-I) domain contains many cysteine and glutamate amino acid residues that are frequently found in various enzyme active sites of DNA nucleases. The I domain, together with the N-terminal, forms the catalytic domain that contains the active site [ (PUBMED:14726017) ].

GO function:nuclease activity (GO:0004518)
Family alignment:
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There are 7650 XPGI domains in 7639 proteins in SMART's nrdb database.

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