Consensus terms for the P4Hc domain

O81759/1-199     PRAIYFPNFA--------TAEQCQAIIERAKVNLK--------PSALALRKGET------
CONSENSUS/80%    ..hhhht.hh..     ...t.ht.lht.hp.......  ....tth.tt..........
CONSENSUS/65%    shhhhhcshh..     .sstphpplhphhpthh....  ...tststps.ttt......
CONSENSUS/50%    Ptlhhhcshl..     .ospcscplhstscsptt...  ...puslpsspsss......


O81759/1-199     ---------AENTKGTRTS-SGTFISASE---------------------ESTGALDFVE
CONSENSUS/80%    ..............th+.......h......      .................h.t.h.
CONSENSUS/65%    ............ssphRt..ththhthtt..      ...............t.hhptlt
CONSENSUS/50%    ...........pssshRss.pssalptpp..      ...............ptltcplp


O81759/1-199     RKIARATMIP------------------------------------------------RS
CONSENSUS/80%    .hhtthh................                       ..............
CONSENSUS/65%    phhpphh................                       ............ht
CONSENSUS/50%    pplpchssh..............                       ..........h.hp


O81759/1-199     HGESFNILRYEL----GQKYDSHYDVFNPTEYGPQS------------------------
CONSENSUS/80%    t...h.hhpYt.....st.h..HhD.........................          
CONSENSUS/65%    pspphplspYsh....Gstat.HhD.h.......................          
CONSENSUS/50%    sspchplssYss....GsaYssHhDtsp.p....................          


O81759/1-199     ----------------SQRIASFLLYLS----------------------DVEEGGETMF
CONSENSUS/80%           ...........p.hohhhahs........... ..........t..tGGthhh
CONSENSUS/65%           ..........pRhhohlhYLs........... ..........ps.pGGthhh
CONSENSUS/50%           .........ssRthTslhYLs........... ..........csppGGshhF


O81759/1-199     PFENGSNMGIGYDY--------KQCIGLKVKPRKGDGLLFYSVFPNGTID----QVNKFM
CONSENSUS/80%    ...t........................tl.s.hsphhha.s..............s.Ht
CONSENSUS/65%    .thth.......................sltPptGphlhahsht...........pshHt
CONSENSUS/50%    sssss......................tsVpPppGsslhahssp...........cohHu


O81759/1-199     LIGALC------CGSNASADFASR
CONSENSUS/80%    shssh........st+h...hah.
CONSENSUS/65%    spslhp.......Gs+hshthWhp
CONSENSUS/50%    usPVhp.......GsRashshWh+

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T