Domains within Drosophila melanogaster protein A1Z9X4_DROME (A1Z9X4)

Hibris, isoform B

Alternative representations: 1 /

Protein length1235 aa
Source databaseUniProt
Identifiers A1Z9X4_DROME, A1Z9X4, FBPP0086545, FBPP0311546, C4IXZ2_DROME, C4IXZ2
Source gene FBgn0029082
Alternative splicing Q8MRA3_DROME, A1Z9X4_DROME

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Bilateria

Predicted functional partners

A1Z9X4_DROME is shown as hbs in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for hbs

Protein A1Z9X4_DROME is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04514Cell adhesion molecules

KEGG orthologous groups

KONameDescription
K06592NECTIN3, PVRL3, CD113poliovirus receptor-related protein 3

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 3 PTMs annotated in this protein:

PTMCount
N-linked glycosylation2
Phosphorylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein hbs.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0311546 in eggNOG.

OGTaxonomic classDescription
FV6U5melanogaster group (species group)Ig_3,C2-set_2,I-set
EJAK4Endopterygota (cohort)nephron
FE1P1melanogaster subgroup (species subgroup)Ig_3,C2-set_2,I-set
LKOG3515All organisms (root)poliovirus receptor-related protein 3,poliovirus receptor-related protein 1,nephron
KOG3515Eukaryota (superkingdom)poliovirus receptor-related protein 3,poliovirus receptor-related protein 1,nephron
HTFJ6Metazoa (kingdom)nephron
HIAEYArthropoda (phylum)nephron
865T3Hexapoda (subphylum)nephron
AGMDINeoptera (infraclass)nephron
ANMZBDiptera (order)Ig_3,C2-set_2,I-set
7ISH7Opisthokonta (clade)nephron
H64XGBilateria (clade)nephron
EH09IDrosophila (genus)Ig_3,C2-set_2,I-set
50GVNSophophora (subgenus)Ig_3,C2-set_2,I-set

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: