Domains within Mus musculus protein DC1I1_MOUSE (O88485)

Cytoplasmic dynein 1 intermediate chain 1

Alternative representations: 1 /

Protein length628 aa
Source databaseUniProt
Identifiers DC1I1_MOUSE, O88485, ENSMUSP00000111221.3, ENSMUSP00000111221, O88486, Q80W09
Source gene ENSMUSG00000029757
Alternative splicing Q3TYJ3_MOUSE, D3Z0M6_MOUSE, DC1I1_MOUSE, O88485-2, D3Z258_MOUSE, A0A0N4SVS1_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

DC1I1_MOUSE is shown as Dync1i1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Dync1i1

Protein DC1I1_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05132Salmonella infection

KEGG orthologous groups

KONameDescription
K10415DYNC1I, DNCIdynein cytoplasmic 1 intermediate chain

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000111221 in eggNOG.

OGTaxonomic classDescription
LKOG1587All organisms (root)dynein cytoplasmic 1 intermediate chain,dynein axonemal intermediate chain 2,dynein axonemal intermediate chain 1
KOG1587Eukaryota (superkingdom)dynein cytoplasmic 1 intermediate chain,dynein axonemal intermediate chain 2,dynein axonemal intermediate chain 1
HUFV8Metazoa (kingdom)dynein cytoplasmic 1 intermediate chain
94231Chordata (phylum)dynein cytoplasmic 1 intermediate chain
5QXS4Sarcopterygii (superclass)dynein cytoplasmic 1 intermediate chain
8Z6S2Mammalia (class)dynein cytoplasmic 1 intermediate chain
4R1PXEuarchontoglires (superorder)dynein cytoplasmic 1 intermediate chain
AI3DKRodentia (order)dynein cytoplasmic 1 intermediate chain
8DGJBMyomorpha (suborder)dynein cytoplasmic 1 intermediate chain
H5FWZBilateria (clade)dynein cytoplasmic 1 intermediate chain
9GJ8GVertebrata (clade)dynein cytoplasmic 1 intermediate chain
7MNQ7Opisthokonta (clade)dynein cytoplasmic 1 intermediate chain
CQG7IMuridae (family)dynein cytoplasmic 1 intermediate chain
ADXDEMurinae (subfamily)dynein cytoplasmic 1 intermediate chain
5PXYWMus (genus)dynein cytoplasmic 1 intermediate chain
HEAU2Mus (subgenus)dynein cytoplasmic 1 intermediate chain

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: