Domains within Homo sapiens protein ENSP00000386556.1

Alternative representations: 1 /

Protein length143 aa
Source databaseEnsembl
Identifiers ENSP00000386556.1, ENSP00000386556
Source gene ENSG00000115468
Alternative splicing ENSP00000386556.1, EFHD1_HUMAN, H7C0I0_HUMAN, Q8WYH2_HUMAN, ENSP00000401073.1, A0A087X1Z2_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

ENSP00000386556.1 is shown as EFHD1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for EFHD1

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9597.ENSPPAP00000016660 in eggNOG.

OGTaxonomic classDescription
LKOG0041All organisms (root)EF-hand domain-containing family member D2,EF-hand domain-containing family member D1
KOG0041Eukaryota (superkingdom)EF-hand domain-containing family member D2,EF-hand domain-containing family member D1
HTP5UMetazoa (kingdom)EF-hand domain-containing family member D2,EF-hand domain-containing family member D1
94VIZChordata (phylum)EF-hand domain-containing family member D1,EF-hand domain-containing family member D2
5R4WUSarcopterygii (superclass)EF-hand domain-containing family member D1,EF-hand domain-containing family member D2
8ZN78Mammalia (class)EF-hand domain-containing family member D1,EF-hand domain-containing family member D2
4RBQ1Euarchontoglires (superorder)EF-hand domain-containing family member D1,EF-hand domain-containing family member D2
4ZYJEPrimates (order)EF-hand domain-containing family member D1
9885SHaplorrhini (suborder)EF-hand domain-containing family member D1
BVBYJSimiiformes (infraorder)EF-hand domain-containing family member D1
9EJFGCatarrhini (parvorder)EF-hand domain-containing family member D1
H5NQ1Bilateria (clade)EF-hand domain-containing family member D2,EF-hand domain-containing family member D1
9FV13Vertebrata (clade)EF-hand domain-containing family member D1,EF-hand domain-containing family member D2
7M7UWOpisthokonta (clade)EF-hand domain-containing family member D2,EF-hand domain-containing family member D1
FX10VHominoidea (superfamily)EF-hand domain-containing family member D1
5N7QYHominidae (family)EF-hand domain-containing family member D1
5Y270Homininae (subfamily)EF-hand domain-containing family member D1

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: