Domains within Homo sapiens protein P38117-2

Isoform 2 of Electron transfer flavoprotein subunit beta

Alternative representations: 1 /

Protein length346 aa
Source databaseUniProt
Identifiers P38117-2, ENSP00000346173.3, ENSP00000346173
Source gene ENSG00000105379
Alternative splicing P38117-2, ETFB_HUMAN, M0QY67_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

P38117-2 is shown as ETFB in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ETFB

Protein P38117-2 is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04144Endocytosis

KEGG orthologous groups

KONameDescription
K03521fixA, etfBelectron transfer flavoprotein beta subunit

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 11 PTMs annotated in this protein:

PTMCount
Acetylation7
Nitrosylation2
Phosphorylation2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein ETFB.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000346173 in eggNOG.

OGTaxonomic classDescription
LCOG2086All organisms (root)electron transfer flavoprotein beta subunit,electron transfer flavoprotein alpha subunit,caffeyl-CoA reductase-Etf complex subunit CarD [EC:1.3.1.108]
KOG3180Eukaryota (superkingdom)electron transfer flavoprotein beta subunit,ADP-ribosylation factor GTPase-activating protein 1
HVM6TMetazoa (kingdom)electron transfer flavoprotein beta subunit
93XKPChordata (phylum)electron transfer flavoprotein beta subunit
5QTIRSarcopterygii (superclass)electron transfer flavoprotein beta subunit
8YYNIMammalia (class)electron transfer flavoprotein beta subunit
4RKYWEuarchontoglires (superorder)electron transfer flavoprotein beta subunit
4ZW6QPrimates (order)electron transfer flavoprotein beta subunit
98DR3Haplorrhini (suborder)electron transfer flavoprotein beta subunit
BVJE7Simiiformes (infraorder)electron transfer flavoprotein beta subunit
9EM79Catarrhini (parvorder)electron transfer flavoprotein beta subunit
H4VJVBilateria (clade)electron transfer flavoprotein beta subunit
7MXAQOpisthokonta (clade)electron transfer flavoprotein beta subunit,ADP-ribosylation factor GTPase-activating protein 1
9GSV8Vertebrata (clade)electron transfer flavoprotein beta subunit
FXAX2Hominoidea (superfamily)electron transfer flavoprotein beta subunit
5NAMIHominidae (family)electron transfer flavoprotein beta subunit
5XW1IHomininae (subfamily)electron transfer flavoprotein beta subunit

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: