Domains within Gallus gallus protein Q91044-6

Isoform KI25 of NT-3 growth factor receptor

Alternative representations: 1 /

Protein length852 aa
Source databaseUniProt
Identifiers Q91044-6, ENSGALP00000049680.1, ENSGALP00000049680
Source gene ENSGALG00000040241
Alternative splicing Q91044-6, NTRK3_CHICK, A0A1D5PSI0_CHICK

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Amniota

Predicted functional partners

Q91044-6 is shown as NTRK3 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for NTRK3

Protein Q91044-6 is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04360Axon guidance
map04020Calcium signaling pathway

KEGG orthologous groups

KONameDescription
K05122ROR1, NTRKR1receptor tyrosine kinase-like orphan receptor 1 [EC:2.7.10.1]
K08852ERN1serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K05101NTRK3, TRKCneurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9031.ENSGALP00000049680 in eggNOG.

OGTaxonomic classDescription
LCOG0478All organisms (root)serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-],RAC serine/threonine-protein kinase [EC:2.7.11.1],pto-interacting protein 1 [EC:2.7.11.1]
KOG1026Eukaryota (superkingdom)receptor tyrosine kinase-like orphan receptor 1 [EC:2.7.10.1],muscle, skeletal, receptor tyrosine kinase [EC:2.7.10.1],PTK7 protein tyrosine kinase 7 [EC:2.7.10.1]
HVF3JMetazoa (kingdom)neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1],neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1],neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
93MTFChordata (phylum)neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1],neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1],neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
5QNRVSarcopterygii (superclass)neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1],neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
6BT7TAves (class)neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]
8R0Y7Neognathae (infraclass)neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]
BIT6SGalloanserae (superorder)neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]
AJ3PNGalliformes (order)neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]
9G88XVertebrata (clade)neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1],neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1],neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
H3JHWBilateria (clade)neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1],neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1],neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
7MRHUOpisthokonta (clade)neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1],neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1],neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
86YI3Phasianidae (family)neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]
9297FPhasianinae (subfamily)neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: