AP4E_app_platf

AP4E_app_platf

Adaptin AP4 complex epsilon appendage platform
SMART ACC:SM001356
Description:This domain is found at the C terminal of clathrin-adaptor epsilon subunit, and at the C-terminus of the appendage on the platform domain.
InterPro ACC:IPR028269
InterPro abstract:

This domain is found in the C-terminal of the AP-4 complex subunit epsilon-1 (AP4E1). Epsilon-1 is a subunit of novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system [ PUBMED:11409905 PUBMED:20972249 expand

Family alignment:View the Family alignment or the Alignment consensus sequence
There are 368 AP4E_app_platf domains in 368 proteins in SMART's NRDB database.

Taxonomic distribution of proteins containing AP4E_app_platf domains

The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing AP4E_app_platf domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.

Relevant references for this domain

Primary literature for the AP4E_app_platf domain is listed below. Automatically-derived, secondary literature is also available.

KEGG pathways involving proteins which contain this domain

This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a AP4E_app_platf domain which could be assigned to a KEGG orthologous group, and not all proteins containing AP4E_app_platf domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.

KEGG pathways

KEGG orthologous groups

Links to other resources describing this domain

PfamAP4E_app_platf
InterProIPR028269