 AerolysinAerolysin toxin | |
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| SMART ACC: | SM000999 |
| Description: | This family represents the pore forming lobe of aerolysin. |
| InterPro ACC: | IPR055267 |
| InterPro abstract: | This entry represents the C-terminal region of Aerolysin from Aeromonas sobria and similar sequences mainly from proteobacteria, animals and plants. This protein is a cytolytic toxin that forms pores in host membranes after proteolytic removal of a C-terminal propeptide, leading to destruction of the membrane permeability barrier and cell death. The pores are formed by transmembrane β-strands … expand |
| GO component: | extracellular region (GO:0005576) |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 81 Aerolysin domains in 81 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing Aerolysin domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing Aerolysin domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
Predicted cellular role
| Cellular role: | Interaction (with the environment) |
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Relevant references for this domain
Primary literature for the Aerolysin domain is listed below. Automatically-derived, secondary literature is also available.