Ala_racemase_C Alanine racemase, C-terminal domain
SMART ACC:	SM001005
Description:	Alanine racemase plays a role in providing the D-alanine required for cell wall biosynthesis by isomerising L-alanine to D-alanine. Proteins contains this domain are found in both prokaryotic and eukaryotic proteins (PUBMED:1676385),(PUBMED:7871888).
InterPro ACC:	IPR011079
InterPro abstract:	Alanine racemase ( EC:5.1.1.1 ) plays a role in providing the D-alanine required for cell wall biosynthesis by isomerising L-alanine to D-alanine. The molecular structure of alanine racemase from Bacillus stearothermophilus (Geobacillus stearothermophilus) was determined by X-ray crystallography to a resolution of 1.9 … expand Alanine racemase ( EC:5.1.1.1 ) plays a role in providing the D-alanine required for cell wall biosynthesis by isomerising L-alanine to D-alanine. The molecular structure of alanine racemase from Bacillus stearothermophilus (Geobacillus stearothermophilus) was determined by X-ray crystallography to a resolution of 1.9 A [ PUBMED:9063881 ]. The alanine racemase monomer is composed of two domains, an eight-stranded α/β barrel at the N terminus, and a C-terminal domain essentially composed of β-strand. This entry represents the C-terminal domain. collapse
Family alignment:	View the Family alignment or the Alignment consensus sequence
There are 25 213 Ala_racemase_C domains in 25 212 proteins in SMART's NRDB database.

Taxonomic distribution of proteins containing Ala_racemase_C domains

The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing Ala_racemase_C domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.

Predicted cellular role

Cellular role:	Metabolic

Relevant references for this domain

Primary literature for the Ala_racemase_C domain is listed below. Automatically-derived, secondary literature is also available.

KEGG pathways involving proteins which contain this domain

This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a Ala_racemase_C domain which could be assigned to a KEGG orthologous group, and not all proteins containing Ala_racemase_C domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.

KEGG pathways

Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

KEGG orthologous groups

Some of these KOs are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

3D structures in PDB containing this domain

Links to other resources describing this domain

Pfam	Ala_racemase_C
InterPro	IPR011079