 AmelinAmeloblastin precursor (Amelin) | |
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| SMART ACC: | SM000817 |
| Description: | This family consists of several mammalian Ameloblastin precursor (Amelin) proteins. Matrix proteins of tooth enamel consist mainly of amelogenin but also of non-amelogenin proteins, which, although their volumetric percentage is low, have an important role in enamel mineralisation. One of the non-amelogenin proteins is ameloblastin, also known as amelin and sheathlin. Ameloblastin (AMBN) is one of the enamel sheath proteins which is though to have a role in determining the prismatic structure of growing enamel crystals. |
| InterPro ACC: | IPR007798 |
| InterPro abstract: | This family consists of mammalian Ameloblastin precursor (Amelin) proteins. Matrix proteins of tooth enamel consist mainly of amelogenin but also of non-amelogenin proteins, which, although their volumetric percentage is low, have an important role in enamel mineralization. One of the non-amelogenin proteins is ameloblastin, also known as amelin and sheathlin. Ameloblastin (AMBN) is one of the … expand |
| GO process: | odontogenesis of dentin-containing tooth (GO:0042475) |
| GO function: | structural constituent of tooth enamel (GO:0030345) |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 130 Amelin domains in 130 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing Amelin domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing Amelin domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
Predicted cellular role
| Cellular role: | Metabolic |
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Relevant references for this domain
Primary literature for the Amelin domain is listed below. Automatically-derived, secondary literature is also available.