BLUF

BLUF

Sensors of blue-light using FAD
SMART ACC:SM001034
Description:The BLUF domain has been shown to bind FAD in the AppA protein (Q53119). AppA is involved in the repression of photosynthesis genes in response to blue-light.
InterPro ACC:IPR007024
InterPro abstract:

The BLUF domain (named for sensors of Blue-Light Using FAD) is an FAD-binding protein domain. BLUF domains are present in various proteins, primarily from bacteria. For example a BLUF domain is found at the N terminus of the AppA protein from Rhodobacter sphaeroides [ PUBMED:16323221 ]. BLUF domains are involved in sensing … expand

GO function:FAD binding (GO:0071949), blue light photoreceptor activity (GO:0009882)
Family alignment:View the Family alignment or the Alignment consensus sequence
There are 5 570 BLUF domains in 5 547 proteins in SMART's NRDB database.

Taxonomic distribution of proteins containing BLUF domains

The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing BLUF domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.

Relevant references for this domain

Primary literature for the BLUF domain is listed below. Automatically-derived, secondary literature is also available.

KEGG pathways involving proteins which contain this domain

This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a BLUF domain which could be assigned to a KEGG orthologous group, and not all proteins containing BLUF domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.

KEGG pathways

Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

KEGG orthologous groups

3D structures in PDB containing this domain

Links to other resources describing this domain

PfamBLUF
InterProIPR007024