 CHASE2 | |
|---|---|
| SMART ACC: | SM001080 |
| Description: | CHASE2 is an extracellular sensory domain, which is present in various classes of transmembrane receptors that are parts of signal transduction pathways in bacteria. Specifically, CHASE2 domains are found in histidine kinases, adenylate cyclases, serine/threonine kinases and predicted diguanylate cyclases/phosphodiesterases. Environmental factors that are recognised by CHASE2 domains are not known at this time (PUBMED:12486065). |
| InterPro ACC: | IPR007890 |
| InterPro abstract: | CHASE2 is an extracellular sensory domain, which is present in various classes of transmembrane receptors that are upstream of signal transduction pathways in bacteria. Specifically, CHASE2 domains are found in histidine kinases, adenylate cyclases, serine/threonine kinases and predicted diguanylate cyclases/phosphodiesterases. The environmental factors that are recognised byCHASE2 domains are … expand |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 9 290 CHASE2 domains in 9 289 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing CHASE2 domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing CHASE2 domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
Predicted cellular role
| Cellular role: | Signalling |
|---|
Relevant references for this domain
Primary literature for the CHASE2 domain is listed below. Automatically-derived, secondary literature is also available.
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a CHASE2 domain which could be assigned to a KEGG orthologous group, and not all proteins containing CHASE2 domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.