CHB_HEX

CHB_HEX

Putative carbohydrate binding domain
SMART ACC:SM001081
Description:This domain represents the N terminal domain in chitobiases and beta-hexosaminidases EC:3.2.1.52. It is composed of a beta sandwich structure that is similar in structure to the cellulose binding domain of cellulase from Cellulomonas fimi (PUBMED:8673609). This suggests that this may be a carbohydrate binding domain.
InterPro ACC:IPR004866
InterPro abstract:

This domain is found in the N terminus of chitobiases and beta-hexosaminidases. It is composed of a β sandwich structure that is similar in structure to the cellulose binding domain of cellulase from Cellulomonas fimi [ PUBMED:8673609 ], suggesting that it may function as a carbohydrate-binding domain.

Family alignment:View the Family alignment or the Alignment consensus sequence
There are 1 494 CHB_HEX domains in 1 480 proteins in SMART's NRDB database.

Taxonomic distribution of proteins containing CHB_HEX domains

The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing CHB_HEX domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.

Predicted cellular role

Cellular role:Metabolic

Relevant references for this domain

Primary literature for the CHB_HEX domain is listed below. Automatically-derived, secondary literature is also available.

KEGG pathways involving proteins which contain this domain

This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a CHB_HEX domain which could be assigned to a KEGG orthologous group, and not all proteins containing CHB_HEX domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.

KEGG pathways

Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

KEGG orthologous groups

Some of these KOs are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

3D structures in PDB containing this domain

Links to other resources describing this domain

PfamCHB_HEX
InterProIPR004866