 CVNH | |
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| SMART ACC: | SM001111 |
| Description: | In molecular biology, the CVNH domain (CyanoVirin-N Homology domain) is a conserved protein domain. It is found in the sugar-binding antiviral protein cyanovirin-N (CVN) as well as proteins from filamentous ascomycetes and in the fern Ceratopteris richardii.(PMID 16003744) |
| InterPro ACC: | IPR011058 |
| InterPro abstract: | Cyanovirin-N (CV-N) is an 11kDa protein from the cyanobacterium Nostoc ellipsosporum that displays virucidal activity against several viruses, including human immunodeficiency virus (AIDS). The virucidal activity of CV-N is mediated through specific high-affinity interactions with the viral surface envelope glycoproteins gp120 and gp41, as well as to high-mannose oligosaccharides found on the … expand |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 347 CVNH domains in 331 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing CVNH domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing CVNH domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
Predicted cellular role
| Cellular role: | Metabolic |
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Relevant references for this domain
Primary literature for the CVNH domain is listed below. Automatically-derived, secondary literature is also available.
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a CVNH domain which could be assigned to a KEGG orthologous group, and not all proteins containing CVNH domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.