 CarD_TRCFCarD-like/TRCF domain | |
|---|---|
| SMART ACC: | SM001058 |
| Description: | CarD is a Myxococcus xanthus protein required for the activation of light- and starvation-inducible genes (PUBMED:8692912). This family includes the presumed N-terminal domain. CarD interacts with the zinc-binding protein CarG, to form a complex that regulates multiple processes in Myxococcus xanthus (PUBMED:16879646). This family also includes a domain to the N-terminal side of the DEAD helicase of TRCF proteins. TRCF displaces RNA polymerase stalled at a lesion, binds to the damage recognition protein UvrA, and increases the template strand repair rate during transcription (PUBMED:7876261). This domain is involved in binding to the stalled RNA polymerase (PUBMED:7876261). |
| InterPro ACC: | IPR003711 |
| InterPro abstract: | This is the RNA polymerase-interacting domain (RID) superfamily of transcription-repair-coupling factor (TRCF), CarD and CarD homologue in Myxococcus xanthus, called CdnL [ PUBMED:23858468 PUBMED:24115125 PUBMED:16469698 … expand |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 27 067 CarD_TRCF domains in 27 067 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing CarD_TRCF domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing CarD_TRCF domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
Relevant references for this domain
Primary literature for the CarD_TRCF domain is listed below. Automatically-derived, secondary literature is also available.
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a CarD_TRCF domain which could be assigned to a KEGG orthologous group, and not all proteins containing CarD_TRCF domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.