 DHDPSDihydrodipicolinate synthetase family | |
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| SMART ACC: | SM001130 |
| Description: | This family has a TIM barrel structure. This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. |
| InterPro ACC: | IPR002220 |
| InterPro abstract: | Dihydrodipicolinate synthase ( EC:4.2.1.52 ) (DHDPS, DapA) catalyses, in higher plants, some fungi and bacteria (gene dapA), the first reaction specific to the biosynthesis of lysine and of diaminopimelate [ PUBMED:22949190 ]. DHDPS is responsible for … expand |
| GO function: | lyase activity (GO:0016829) |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 57 397 DHDPS domains in 57 392 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing DHDPS domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing DHDPS domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
Predicted cellular role
| Cellular role: | Metabolic |
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Relevant references for this domain
Primary literature for the DHDPS domain is listed below. Automatically-derived, secondary literature is also available.
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a DHDPS domain which could be assigned to a KEGG orthologous group, and not all proteins containing DHDPS domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.