 DIRP | |
|---|---|
| SMART ACC: | SM001135 |
| Description: | DIRP (Domain in Rb-related Pathway) is postulated to be involved in the Rb-related pathway, which is encoded by multiple eukaryotic genomes and is present in proteins including lin-9 of Caenorhabditis elegans, aly of fruit fly and mustard weed. Studies of lin-9 and aly of fruit fly proteins containing DIRP suggest that this domain might be involved in development. Aly, lin-9, act in parallel to, or downstream of, activation of MAPK by the RTK-Ras signalling pathway. |
| InterPro ACC: | IPR033471 |
| InterPro abstract: | DIRP (Domain in Rb-related Pathway) is postulated to be involved in the Rb-related pathway, which is encoded by multiple eukaryotic genomes and is present in proteins including lin-9 of Caenorhabditis elegans, aly of fruit fly and mustard weed. Studies of lin-9 and aly of fruit fly proteins containing DIRP suggest that this domain might be involved in development. Aly, lin-9, act in parallel … expand |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 1 221 DIRP domains in 1 219 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing DIRP domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing DIRP domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
Relevant references for this domain
Primary literature for the DIRP domain is listed below. Automatically-derived, secondary literature is also available.
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a DIRP domain which could be assigned to a KEGG orthologous group, and not all proteins containing DIRP domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.