 DUF1716Eukaryotic domain of unknown function (DUF1716) | |
|---|---|
| SMART ACC: | SM001156 |
| Description: | This domain is found in eukaryotic proteins. A human nuclear protein with this domain (Q8WYA6) is thought to have a role in apoptosis [(PUBMED:12659813)]. |
| InterPro ACC: | IPR013180 |
| InterPro abstract: | This entry represents the N-terminal domain of the beta-catenin-like protein 1 (CTNNBL1). CTNNBL1 is a component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. In humans, it participates in AID/AICDA-mediated Ig class switching recombination (CSR) and may induce apoptosis [ PUBMED:12659813 … expand |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 1 502 DUF1716 domains in 1 499 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing DUF1716 domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing DUF1716 domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
Relevant references for this domain
Primary literature for the DUF1716 domain is listed below. Automatically-derived, secondary literature is also available.
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a DUF1716 domain which could be assigned to a KEGG orthologous group, and not all proteins containing DUF1716 domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.