 FDX-ACBFerredoxin-fold anticodon binding domain | |
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| SMART ACC: | SM000896 |
| Description: | This is the anticodon binding domain found in some phenylalanyl tRNA synthetases. The domain has a ferredoxin fold, consisting of an alpha+beta sandwich with anti-parallel beta-sheets (beta-alpha-beta x2). |
| InterPro ACC: | IPR005121 |
| InterPro abstract: | Aminoacyl-tRNA synthetases (aaRSs) play a crucial role in the translation of the genetic code by means of covalent attachment of amino acids to their cognate tRNAs. Phenylalanine-tRNA synthetase (PheRS, also known as Phenylalanine-tRNA ligase) is known to be among the most complex enzymes of the aaRS family. Bacterial and mitochondrial PheRSs share a ferredoxin-fold anticodon binding (FDX-ACB) … expand |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 24 139 FDX-ACB domains in 24 139 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing FDX-ACB domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing FDX-ACB domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
Predicted cellular role
| Cellular role: | Translation |
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Relevant references for this domain
Primary literature for the FDX-ACB domain is listed below. Automatically-derived, secondary literature is also available.
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a FDX-ACB domain which could be assigned to a KEGG orthologous group, and not all proteins containing FDX-ACB domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.