 IROMotif in Iroquois-class homeodomain proteins (only). Unknown function. | |
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| SMART ACC: | SM000548 |
| Description: | - |
| InterPro ACC: | IPR003893 |
| InterPro abstract: | This is a motif found only in Iroquois-class homeodomain proteins. It has unknown function. Examples include iroquois-class homeodomain protein IRX-4, and homeobox proteins caupolican and araucan, which control proneural and vein forming genesand are positive transcriptional controllers of achaete-scute. They may act as activators that interact with the transcriptional initiation complex assembled … expand |
| GO process: | regulation of DNA-templated transcription (GO:0006355) |
| GO component: | nucleus (GO:0005634) |
| GO function: | DNA binding (GO:0003677) |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 1 828 IRO domains in 1 815 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing IRO domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing IRO domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
Relevant references for this domain
Primary literature for the IRO domain is listed below. Automatically-derived, secondary literature is also available.
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a IRO domain which could be assigned to a KEGG orthologous group, and not all proteins containing IRO domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.
KEGG pathways
KEGG orthologous groups
Links to other resources describing this domain
| InterPro | IPR003893 |
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