MORN Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases.
SMART ACC:	SM000698
Description:	-
InterPro ACC:	IPR003409
InterPro abstract:	This entry represents MORN (Membrane Occupation and Recognition Nexus) repeat. This repeat was identified in multiple copies in several proteins including junctophilins [ PUBMED:10949023 ]. More recently it was found that MORN repeat proteins are quite ubiquitous and are present in both eukaryotes and prokaryotes. The … expand This entry represents MORN (Membrane Occupation and Recognition Nexus) repeat. This repeat was identified in multiple copies in several proteins including junctophilins [ PUBMED:10949023 ]. More recently it was found that MORN repeat proteins are quite ubiquitous and are present in both eukaryotes and prokaryotes. The number of MORN repeats in any given protein can vary greatly, from 2 to over 20, and they are found in combination with a wide range of other domains. MORN repeats are generally assumed to be lipid-binding modules. Structurally, MORN repeat is composed of a β-hairpin followed by a short loop that connects to the next MORN repeat [ PUBMED:33296386 PUBMED:31279628 ]. collapse
Family alignment:	View the Family alignment or the Alignment consensus sequence
There are 113 928 MORN domains in 17 959 proteins in SMART's NRDB database.

Taxonomic distribution of proteins containing MORN domains

The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing MORN domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.

Relevant references for this domain

Primary literature for the MORN domain is listed below. Automatically-derived, secondary literature is also available.

KEGG pathways involving proteins which contain this domain

This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a MORN domain which could be assigned to a KEGG orthologous group, and not all proteins containing MORN domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.

KEGG pathways

Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

KEGG orthologous groups

Some of these KOs are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

3D structures in PDB containing this domain

Links to other resources describing this domain

InterPro	IPR003409