 N1221N1221-like protein | |
|---|---|
| SMART ACC: | SM001292 |
| Description: | The sequences featured in this family are similar to a hypothetical protein product of ORF N1221 in the CPT1-SPC98 intergenic region of the yeast genome . This encodes an acidic polypeptide with several possible transmembrane regions PMID:8619318. |
| InterPro ACC: | IPR012486 |
| InterPro abstract: | This domain can be found in the N terminus of the yeast Far11 protein and the human STRP1/2 proteins. Budding yeast Far11 interacts with the phosphatases Pph21, Pph22, and Pph3 and may be involved in the regulation of autophagy and the DNA damage signaling [ PUBMED:22782902 ]. STRP1/2 (also known as FAM40A/B) … expand |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 1 653 N1221 domains in 1 652 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing N1221 domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing N1221 domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
Relevant references for this domain
Primary literature for the N1221 domain is listed below. Automatically-derived, secondary literature is also available.
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a N1221 domain which could be assigned to a KEGG orthologous group, and not all proteins containing N1221 domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.