 NOD | |
|---|---|
| SMART ACC: | SM001338 |
| Description: | NOTCH signalling plays a fundamental role during a great number of developmental processes in multicellular animals (PMID:10221902, 11112321). NOD and NODP represent a region present in many NOTCH proteins and NOTCH homologs in multiple species such as NOTCH2 and NOTCH3, LIN12, SC1 and TAN1. Role of NOD domain remains to be elucidated. |
| InterPro ACC: | IPR010660 |
| InterPro abstract: | NOTCH signalling plays a fundamental role during a great number of developmental processes in multicellular animals [ PUBMED:10221902 ]. NOD (NOTCH protein domain) represents a region present in many NOTCH proteins and NOTCH homologues in multiple species such as 0, NOTCH2 and NOTCH3, LIN12, SC1 and TAN1. Role of NOD … expand |
| GO process: | cell differentiation (GO:0030154) |
| GO component: | membrane (GO:0016020) |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 1 409 NOD domains in 1 408 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing NOD domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing NOD domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
Relevant references for this domain
Primary literature for the NOD domain is listed below. Automatically-derived, secondary literature is also available.
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a NOD domain which could be assigned to a KEGG orthologous group, and not all proteins containing NOD domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.