 PKDRepeats in polycystic kidney disease 1 (PKD1) and other proteins | |
|---|---|
| SMART ACC: | SM000089 |
| Description: | Polycystic kidney disease 1 protein contains 14 repeats, present elsewhere such as in microbial collagenases. |
| InterPro ACC: | IPR022409 |
| InterPro abstract: | The PKD (Polycystic Kidney Disease) domain was first identified in the Polycystic Kidney Disease protein, polycystin-1 (PDK1 gene), and contains an Ig-like fold consisting of a β-sandwich of seven strands in two sheets with a Greek key topology, although some members have additional strands [ PUBMED:9889186 ]. Polycystin-1 … expand |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 95 746 PKD domains in 42 890 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing PKD domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing PKD domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
Relevant references for this domain
Primary literature for the PKD domain is listed below. Automatically-derived, secondary literature is also available.
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a PKD domain which could be assigned to a KEGG orthologous group, and not all proteins containing PKD domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.