Rho_N

Rho_N

Rho termination factor, N-terminal domain
SMART ACC:SM000959
Description:The Rho termination factor disengages newly transcribed RNA from its DNA template at certain, specific transcripts. It it thought that two copies of Rho bind to RNA and that Rho functions as a hexamer of protomers (PUBMED:10230401). This domain is found to the N-terminus of the RNA binding domain.
InterPro ACC:IPR011112
InterPro abstract:

The Rho termination factor disengages newly transcribed RNA from its DNA template at certain, specific transcripts. It is thought that two copies of Rho bind to RNA and that Rho functions as a hexamer of protomers [ PUBMED:10230401 ]. This domain is found to the N terminus of the RNA binding domain ( expand

GO process:DNA-templated transcription termination (GO:0006353)
Family alignment:View the Family alignment or the Alignment consensus sequence
There are 12 788 Rho_N domains in 12 697 proteins in SMART's NRDB database.

Taxonomic distribution of proteins containing Rho_N domains

The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing Rho_N domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.

Predicted cellular role

Cellular role:Transcription

Relevant references for this domain

Primary literature for the Rho_N domain is listed below. Automatically-derived, secondary literature is also available.

KEGG pathways involving proteins which contain this domain

This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a Rho_N domain which could be assigned to a KEGG orthologous group, and not all proteins containing Rho_N domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.

KEGG pathways

Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

KEGG orthologous groups

Some of these KOs are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

3D structures in PDB containing this domain

Links to other resources describing this domain

InterProIPR011112
PfamRho_N