 HA2Helicase associated domain (HA2) Add an annotation | |
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| SMART ACC: | SM000847 |
| Description: | This presumed domain is about 90 amino acid residues in length. It is found is a diverse set of RNA helicases. Its function is unknown, however it seems likely to be involved in nucleic acid binding. |
| InterPro ACC: | IPR007502 |
| InterPro abstract: | This is the helicase associated domain (HA2) found as a diverse set of RNA helicases. It has an all α-helical fold that can be divided in two subdomains, an N-terminal degenerated winged helix (WH) and a C-terminal ratchet-like domain [ PUBMED:26545078 PUBMED:31409651 … expand |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 38 456 HA2 domains in 38 427 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing HA2 domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing HA2 domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
Predicted cellular role
| Cellular role: | Translation |
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KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a HA2 domain which could be assigned to a KEGG orthologous group, and not all proteins containing HA2 domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.