The Pfam:RyR domain within your query sequence starts at position 851 and ends at position 945, and its E-value is 6.5e-33.

DFVPCPVDTIQIVLPPHLERIREKLAENIHELWALTRIEQGWTYGPVRDDNKRLHPCLVNFHSLPEPERNYNLQMSGETLKTLLALGCHVGMADE
Pfam:RyR

Pfam:RyR
Pfam domain

Pfam ACC: