The Pfam:I-set domain within your query sequence starts at position 2054 and ends at position 2139, and its E-value is 6.2e-8.

DHFSQGLTDTEVQLGEAAIVSCTLASDLGPGTWFKDGVKLTAQDGVIFEQDGLTHRLILTHVEGTQAGKYTFVAGCQHSEASLTVQ
Pfam:I-set

Pfam:I-set
Pfam domain

Pfam ACC: