 6PGD6-phosphogluconate dehydrogenase, C-terminal domain | |
|---|---|
| SMART ACC: | SM001350 |
| Description: | This family represents the C-terminal all-alpha domain of 6-phosphogluconate dehydrogenase. The domain contains two structural repeats of 5 helices each. |
| InterPro ACC: | IPR006114 |
| InterPro abstract: | 6-Phosphogluconate dehydrogenase ( EC:1.1.1.44 ) (6PGD) is an oxidative carboxylase that catalyses the decarboxylating reduction of 6-phosphogluconate into ribulose 5-phosphate in the presence of NADP. This reaction is a component of the hexose mono-phosphate shunt and pentose phosphate pathways (PPP) [ PUBMED:2113917 … expand |
| GO process: | pentose-phosphate shunt (GO:0006098) |
| GO function: | phosphogluconate dehydrogenase (decarboxylating) activity (GO:0004616) |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 19 935 6PGD domains in 19 931 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing 6PGD domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing 6PGD domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a 6PGD domain which could be assigned to a KEGG orthologous group, and not all proteins containing 6PGD domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.