Ami_2

Ami_2

SMART ACC:SM000644
Description: -
InterPro ACC:IPR002502
InterPro abstract:

Proteins containing this domain include zinc amidases that have N-acetylmuramoyl-L-alanine amidase activity EC:3.5.1.28. This enzyme domain cleaves the amide bond between N-acetylmuramoyl and L-amino acids in bacterial cell walls (preferentially: D-lactyl-L-Ala). The bacteriophage endolysins PLY118 and PLY500 cleave between … expand

GO process:peptidoglycan catabolic process (GO:0009253)
GO function:N-acetylmuramoyl-L-alanine amidase activity (GO:0008745)
Family alignment:View the Family alignment or the Alignment consensus sequence
There are 27 919 Ami_2 domains in 27 615 proteins in SMART's NRDB database.

Taxonomic distribution of proteins containing Ami_2 domains

The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing Ami_2 domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.

KEGG pathways involving proteins which contain this domain

This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a Ami_2 domain which could be assigned to a KEGG orthologous group, and not all proteins containing Ami_2 domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.

KEGG pathways

Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

KEGG orthologous groups

Some of these KOs are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

3D structures in PDB containing this domain

Links to other resources describing this domain

InterProIPR002502
PfamAmidase_2