 DUF1086Domain of Unknown Function (DUF1086) | |
|---|---|
| SMART ACC: | SM001146 |
| Description: | This family consists of several eukaryotic domains of unknown function which are present in chromodomain helicase DNA binding proteins. This domain is often found in conjunction with DEXDc (SM00487), HELICc (SM00490), DUF1087,CHROMO (SM00298) and PHD (SM00249). |
| InterPro ACC: | IPR009462 |
| InterPro abstract: | CHD proteins (name derived from the presence of a Chromodomain, SWI2/SNF2 ATPase/Helicase and a motif with sequence similarity to a DNA-binding domain) are ATP-dependent chromatin remodelers found in plant and animals. In eukaryotes, there are three subfamilies, I, II and III. This domain is found in members of subfamily II which play a role in repression of genes involved in developmental regulation … expand |
| GO process: | chromatin remodeling (GO:0006338) |
| GO function: | DNA binding (GO:0003677) |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 1 985 DUF1086 domains in 1 982 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing DUF1086 domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing DUF1086 domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a DUF1086 domain which could be assigned to a KEGG orthologous group, and not all proteins containing DUF1086 domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.