DUF1237

DUF1237

SMART ACC:SM001149
Description:This family contains a number of hypothetical proteins of about 450 residues in length. Their function is unknown, and most are bacterial. However, structurally this family is part of the 6 hairpin glycosidase superfamily, suggesting a glycosyl hydrolase function.
InterPro ACC:IPR008313
InterPro abstract:

This family includes proteins from bacteria and fungi. It was originally identified as a protein of unknown function from Schizosaccharomyces pombe, which was isolated from a screen to identify novel genes required for meiosis [ PUBMED:16303567 ]. Members of this family have since been characterised from Streptococcus … expand

Family alignment:View the Family alignment or the Alignment consensus sequence
There are 3 685 DUF1237 domains in 3 685 proteins in SMART's NRDB database.

Taxonomic distribution of proteins containing DUF1237 domains

The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing DUF1237 domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.

KEGG pathways involving proteins which contain this domain

This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a DUF1237 domain which could be assigned to a KEGG orthologous group, and not all proteins containing DUF1237 domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.

KEGG pathways

Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

KEGG orthologous groups

Some of these KOs are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

3D structures in PDB containing this domain

Links to other resources describing this domain

InterProIPR008313
PfamDUF1237