 DUF1338 | |
|---|---|
| SMART ACC: | SM001150 |
| Description: | This domain is found in a variety of bacterial and fungal hypothetical proteins of unknown function. The structure of this domain has been solved by structural genomics. The structure implies a zinc-binding function, so it is a putative metal hydrolase (PDB:3iuz). |
| InterPro ACC: | IPR009770 |
| InterPro abstract: | This entry represents a group of bacterial, fungal and plant sequences, including 2-oxoadipate dioxygenase/decarboxylase (referred to as HGLS and YdcJ) from Escherichia coli. YdcJ, which is involved in D-lysine metabolism, catalyses a successive decarboxylation and intramolecular hydroxylation of 2-oxoadipate forming 2-hydroxyglutarate in a Fe(II) and oxygen-dependent manner. Members of this … expand |
| GO function: | oxidoreductase activity (GO:0016491) |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 4 886 DUF1338 domains in 4 886 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing DUF1338 domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing DUF1338 domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a DUF1338 domain which could be assigned to a KEGG orthologous group, and not all proteins containing DUF1338 domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.