 ENT | |
|---|---|
| SMART ACC: | SM001191 |
| Description: | This presumed domain is named after Emsy N Terminus (ENT). Emsy is a protein that is amplified in breast cancer and interacts with BRCA2. The N terminus of this protein is found to be similar to other vertebrate and plant proteins of unknown function. This domain has a completely conserved histidine residue that may be functionally important. |
| InterPro ACC: | IPR005491 |
| InterPro abstract: | The EMSY N-terminal (ENT) domain is a ~90-residue module, which is unique in the human proteome, although multiple copies are found in Arabidopsis proteins. In the plant proteins, the ENT domains are accompanied by Agenet domains, plant specific homologues of Tudor domains [ PUBMED:14651845 PUBMED:12575993 … expand |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 2 347 ENT domains in 2 318 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing ENT domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing ENT domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a ENT domain which could be assigned to a KEGG orthologous group, and not all proteins containing ENT domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.