 FeoA | |
|---|---|
| SMART ACC: | SM000899 |
| Description: | This entry represents the core domain of the ferrous iron (Fe2+) transport protein FeoA found in bacteria. This domain also occurs at the C-terminus in related proteins. The transporter Feo is composed of three proteins: FeoA a small, soluble SH3-domain protein probably located in the cytosol; FeoB, a large protein with a cytosolic N-terminal G-protein domain and a C-terminal integral inner-membrane domain containing two 'Gate' motifs which likely functions as the Fe2+ permease; and FeoC, a small protein apparently functioning as an [Fe-S]-dependent transcriptional repressor. Feo allows the bacterial cell to acquire iron from its environment. |
| InterPro ACC: | IPR007167 |
| InterPro abstract: | This entry represents the core domain of the ferrous iron (Fe2+) transport protein FeoA found in bacteria. This domain also occurs at the C terminus in related proteins. This suggests that this domain may be metal-binding. In most cases this is likely to be either iron or manganese. The transporter Feo is composed of three proteins: FeoA a small, soluble SH3-domain protein probably located … expand |
| GO function: | transition metal ion binding (GO:0046914) |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 20 657 FeoA domains in 20 026 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing FeoA domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing FeoA domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
Predicted cellular role
| Cellular role: |
|---|
Relevant references for this domain
Primary literature for the FeoA domain is listed below. Automatically-derived, secondary literature is also available.
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a FeoA domain which could be assigned to a KEGG orthologous group, and not all proteins containing FeoA domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.