FtsA

FtsA

Cell division protein FtsA
SMART ACC:SM000842
Description:FtsA is essential for bacterial cell division, and co-localizes to the septal ring with FtsZ. It has been suggested that the interaction of FtsA-FtsZ has arisen through coevolution in different bacterial strains (PUBMED:9352931).
InterPro ACC:IPR003494
InterPro abstract:

FtsA is essential for bacterial cell division, and co-localises to the septal ring with FtsZ. The SHS2 domain, also known as subdomain 1C [ PUBMED:22473211 ], is inserted into the RNAseH fold of FtsA [ PUBMED:15281131 ], and is involved in protein-protein … expand

GO process:cell division (GO:0051301)
GO function:protein binding (GO:0005515)
Family alignment:View the Family alignment or the Alignment consensus sequence
There are 14 427 FtsA domains in 14 427 proteins in SMART's NRDB database.

Taxonomic distribution of proteins containing FtsA domains

The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing FtsA domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.

Predicted cellular role

Cellular role:Replication

KEGG pathways involving proteins which contain this domain

This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a FtsA domain which could be assigned to a KEGG orthologous group, and not all proteins containing FtsA domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.

KEGG pathways

Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

KEGG orthologous groups

Some of these KOs are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

3D structures in PDB containing this domain

Links to other resources describing this domain

InterProIPR003494
PfamFtsA