 HintCHint (Hedgehog/Intein) domain C-terminal region | |
|---|---|
| SMART ACC: | SM000305 |
| Description: | Hedgehog/Intein domain, C-terminal region. Domain has been split to accommodate large insertions of endonucleases. |
| InterPro ACC: | IPR003586 |
| InterPro abstract: | This entry represents the C-terminal region of the hint domain. Hedgehog proteins are a family of secreted signal molecules required for embryonic cell differentiation. They are synthesised as inactive precursors with an N-terminal signalling domain linked to a C-terminal autoprocessing domain. The three-dimensional structure of the autolytic domain of the hedgehog protein of shows similarity … expand |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 6 421 HintC domains in 5 853 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing HintC domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing HintC domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a HintC domain which could be assigned to a KEGG orthologous group, and not all proteins containing HintC domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.