IENR2

IENR2

Intron-encoded nuclease repeat 2
SMART ACC:SM000496
Description:Short helical motif of unknown function (unpublished results).
InterPro ACC:IPR003611
InterPro abstract:

NUMOD3 (nuclease associated modular domain 3) is a DNA-binding motif found in homing endonucleases and related proteins. It occurs on its own or in tandem repeats in GIY-YIG and HTH proteins. It constitutes a β-turn-loop-helix subregion of the the DNA-binding domain of I-TevI homing endonuclease ( P13299 ) [ expand

GO function:DNA binding (GO:0003677)
Family alignment:View the Family alignment or the Alignment consensus sequence
There are 5 015 IENR2 domains in 1 625 proteins in SMART's NRDB database.

Taxonomic distribution of proteins containing IENR2 domains

The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing IENR2 domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.

Relevant references for this domain

Primary literature for the IENR2 domain is listed below. Automatically-derived, secondary literature is also available.

KEGG pathways involving proteins which contain this domain

This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a IENR2 domain which could be assigned to a KEGG orthologous group, and not all proteins containing IENR2 domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.

KEGG pathways

Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

KEGG orthologous groups

Some of these KOs are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

3D structures in PDB containing this domain

Links to other resources describing this domain

InterProIPR003611