LytTR

LytTR

LytTr DNA-binding domain
SMART ACC:SM000850
Description:This domain is found in a variety of bacterial transcriptional regulators. The domain binds to a specific DNA sequence pattern.
InterPro ACC:IPR007492
InterPro abstract:

The LytTR domain is a DNA-binding, potential winged helix-turn-helix (wHTH) domain of about 100 amino acids, present in bacterial transcriptional regulators of the algR/agrA/lytR family. It is named after Bacillus subtilis LytT and Staphylococcus aureus lytR response regulators, involved in the regulation of cell autolysis [ PUBMED:12034833 expand

GO function:DNA binding (GO:0003677)
Family alignment:View the Family alignment or the Alignment consensus sequence
There are 46 828 LytTR domains in 46 828 proteins in SMART's NRDB database.

Taxonomic distribution of proteins containing LytTR domains

The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing LytTR domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.

Predicted cellular role

Cellular role:Transcription

Relevant references for this domain

Primary literature for the LytTR domain is listed below. Automatically-derived, secondary literature is also available.

KEGG pathways involving proteins which contain this domain

This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a LytTR domain which could be assigned to a KEGG orthologous group, and not all proteins containing LytTR domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.

KEGG pathways

Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

KEGG orthologous groups

Some of these KOs are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

3D structures in PDB containing this domain

Links to other resources describing this domain

PfamLytTR
InterProIPR007492