N-glycanase_N Peptide-N-glycosidase F, N terminal
SMART ACC:	SM001290
Description:	Members of this family adopt an eight-stranded antiparallel beta jelly roll configuration, with the beta strands arranged into two sheets. They are similar in topology to many viral capsid proteins, as well as lectins and several glucanases. The domain allows the protein to bind sugars and catalyses the complete removal of N-linked oligosaccharide chains from glycoproteins PMID:7881905.
InterPro ACC:	IPR015196
InterPro abstract:	This domain adopts an eight-stranded antiparallel β jelly roll configuration, with the β strands arranged into two sheets. It is similar in topology to many viral capsid proteins, as well as lectins and several glucanases. This domain allows the protein to bind sugars and catalyses the complete removal of N-linked oligosaccharide chains from glycoproteins [ PUBMED:7881905 … expand This domain adopts an eight-stranded antiparallel β jelly roll configuration, with the β strands arranged into two sheets. It is similar in topology to many viral capsid proteins, as well as lectins and several glucanases. This domain allows the protein to bind sugars and catalyses the complete removal of N-linked oligosaccharide chains from glycoproteins [ PUBMED:7881905 ]. collapse
Family alignment:	View the Family alignment or the Alignment consensus sequence
There are 261 N-glycanase_N domains in 260 proteins in SMART's NRDB database.

Taxonomic distribution of proteins containing N-glycanase_N domains

The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing N-glycanase_N domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.

KEGG pathways involving proteins which contain this domain

This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a N-glycanase_N domain which could be assigned to a KEGG orthologous group, and not all proteins containing N-glycanase_N domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.

KEGG pathways

KEGG orthologous groups

Some of these KOs are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

3D structures in PDB containing this domain

Links to other resources describing this domain

Pfam	N-glycanase_N
InterPro	IPR015196