This entry represents a putative carbohydrate binding module (NPCBM) domain found at the N terminus of glycosyl hydrolase family 98 proteins [ PUBMED:16212961 ].

Proteins containing this domain include CpGH98 from C. perfringens. It specifically hydrolyses fucose-containing trisaccharides from the glycotopes … expand

This entry represents a putative carbohydrate binding module (NPCBM) domain found at the N terminus of glycosyl hydrolase family 98 proteins [ PUBMED:16212961 ].

Proteins containing this domain include CpGH98 from C. perfringens. It specifically hydrolyses fucose-containing trisaccharides from the glycotopes of blood groups A and B and is implicated for the infectivity and virulence of this pathogen [ PUBMED:15618227 ]. CpGH98 has a central TIM barrel catalytic domain, in which putative catalytic residues may be tentatively identified, and an N-terminal novel putative carbohydrate binding module (NPCBM) [ PUBMED:15618227 ].

NPCBM domains found in bacterial conflict systems are predicted to interact with invasive molecules and recruit downstream effectors [ PUBMED:34061031 ].