 Nbs1_CDNA damage repair protein Nbs1 | |
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| SMART ACC: | SM001348 |
| Description: | This C terminal region of the DNA damage repair protein Nbs1 has been identified to be necessary for the binding of Mre11 and Tel1 (PMID:15964794). |
| InterPro ACC: | IPR013908 |
| InterPro abstract: | This is the C-terminal region of Nibrin (also known as DNA damage repair protein Nbs1) that has been identified to be necessary for the binding of Mre11 and Tel1 [ PUBMED:15964794 ]. Nibrin (also known as Nbs1 or p95) plays an important role in the DNA damage response (DDR) and DNA repair. It is part of the … expand |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 355 Nbs1_C domains in 354 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing Nbs1_C domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing Nbs1_C domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
Predicted cellular role
| Cellular role: | Replication |
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Relevant references for this domain
Primary literature for the Nbs1_C domain is listed below. Automatically-derived, secondary literature is also available.
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a Nbs1_C domain which could be assigned to a KEGG orthologous group, and not all proteins containing Nbs1_C domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.