 PIG-XPIG-X / PBN1 | |
|---|---|
| SMART ACC: | SM000780 |
| Description: | Mammalian PIG-X and yeast PBN1 are essential components of glycosylphosphatidylinositol-mannosyltransferase I. These enzymes are involved in the transfer of sugar molecules. |
| InterPro ACC: | IPR013233 |
| InterPro abstract: | Mammalian PIG-X and yeast PBN1 are essential components of glycosylphosphatidylinositol-mannosyltransferase I [ PUBMED:15635094 ]. These enzymes are involved in the transfer of sugar molecules. They probably act by stabilizing the mannosyltransferase PIG-M (GPI14 in yeast) [ PUBMED:15635094 … expand |
| GO process: | GPI anchor biosynthetic process (GO:0006506) |
| GO component: | endoplasmic reticulum membrane (GO:0005789) |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 1 054 PIG-X domains in 1 054 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing PIG-X domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing PIG-X domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
Predicted cellular role
| Cellular role: | Metabolic |
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KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a PIG-X domain which could be assigned to a KEGG orthologous group, and not all proteins containing PIG-X domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.