Prim-Pol

Prim-Pol

Bifunctional DNA primase/polymerase, N-terminal
SMART ACC:SM000943
Description:Members of this family adopt a structure consisting of a core of antiparallel beta sheets. They are found in various bacterial hypothetical proteins, and have been shown to harbour both primase and polymerase activities (PUBMED:14730355).
InterPro ACC:IPR015330
InterPro abstract:

Members of this family adopt a structure consisting of a core of antiparallel β sheets. They are found in various bacterial hypothetical proteins, and have been shown to harbour both primase and polymerase activities [ PUBMED:14730355 ].

Family alignment:View the Family alignment or the Alignment consensus sequence
There are 9 307 Prim-Pol domains in 9 303 proteins in SMART's NRDB database.

Taxonomic distribution of proteins containing Prim-Pol domains

The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing Prim-Pol domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.

Predicted cellular role

Cellular role:Transport

KEGG pathways involving proteins which contain this domain

This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a Prim-Pol domain which could be assigned to a KEGG orthologous group, and not all proteins containing Prim-Pol domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.

KEGG pathways

Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

KEGG orthologous groups

Some of these KOs are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

3D structures in PDB containing this domain

Links to other resources describing this domain

PfamPrim-Pol
InterProIPR015330