RFX5_DNA_bdg RFX5 DNA-binding domain
SMART ACC:	SM001306
Description:	RFX5 and RFXAP reveals molecular details associated with MHCII gene expression.
InterPro ACC:	IPR029298
InterPro abstract:	Transcription of all the members of MHCII family of genes is controlled by a set of conserved transcription factors and promoter elements. One of these class II transactivators is the DNA-binding RFX complex, which consists of subunits RFX5 and its accessory proteins RFXAP and RFXANK [ PUBMED:10779326 ]. This … expand Transcription of all the members of MHCII family of genes is controlled by a set of conserved transcription factors and promoter elements. One of these class II transactivators is the DNA-binding RFX complex, which consists of subunits RFX5 and its accessory proteins RFXAP and RFXANK [ PUBMED:10779326 ]. This entry represents the C-terminal domain of RFX5. The C-terminal domain mediates cooperative binding between the RFX complex and NF-Y, a transcription factor binding to the Y box sequence of MHC-II promoters [ PUBMED:10779326 ]. collapse
Family alignment:	View the Family alignment or the Alignment consensus sequence
There are 128 RFX5_DNA_bdg domains in 128 proteins in SMART's NRDB database.

Taxonomic distribution of proteins containing RFX5_DNA_bdg domains

The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing RFX5_DNA_bdg domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.

KEGG pathways involving proteins which contain this domain

This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a RFX5_DNA_bdg domain which could be assigned to a KEGG orthologous group, and not all proteins containing RFX5_DNA_bdg domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.

KEGG pathways

KEGG orthologous groups

Links to other resources describing this domain

InterPro	IPR029298
Pfam	RFX5_DNA_bdg