 SMC_hingeSMC proteins Flexible Hinge Domain | |
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| SMART ACC: | SM000968 |
| Description: | This entry represents the hinge region of the SMC (Structural Maintenance of Chromosomes) family of proteins. The hinge region is responsible for formation of the DNA interacting dimer. It is also possible that the precise structure of it is an essential determinant of the specificity of the DNA-protein interaction (PUBMED:12411491). |
| InterPro ACC: | IPR010935 |
| InterPro abstract: | This entry represents the hinge region of the SMC (Structural Maintenance of Chromosomes) family of proteins. The hinge region is responsible for formation of the DNA interacting dimer. It is also possible that its precise structure is an essential determinant of the specificity of the DNA-protein interaction [ PUBMED:12411491 … expand |
| GO process: | chromosome organization (GO:0051276) |
| GO component: | chromosome (GO:0005694) |
| GO function: | protein binding (GO:0005515), ATP binding (GO:0005524) |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 21 778 SMC_hinge domains in 21 762 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing SMC_hinge domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing SMC_hinge domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
Predicted cellular role
| Cellular role: | Transport |
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Relevant references for this domain
Primary literature for the SMC_hinge domain is listed below. Automatically-derived, secondary literature is also available.
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a SMC_hinge domain which could be assigned to a KEGG orthologous group, and not all proteins containing SMC_hinge domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.