SecA_PP_bind SecA preprotein cross-linking domain
SMART ACC:	SM000958
Description:	The SecA ATPase is involved in the insertion and retraction of preproteins through the plasma membrane. This domain has been found to cross-link to preproteins, thought to indicate a role in preprotein binding. The pre-protein cross-linking domain is comprised of two sub domains that are inserted within the ATPase domain (PUBMED:12242434).
InterPro ACC:	IPR011130
InterPro abstract:	The SecA ATPase is involved in the insertion and retraction of preproteins through the plasma membrane. This domain has been found to cross-link to preproteins, thought to indicate a role in preprotein binding. The pre-protein cross-linking domain is comprised of two sub domains that are inserted within the ATPase domain [ PUBMED:12242434 … expand The SecA ATPase is involved in the insertion and retraction of preproteins through the plasma membrane. This domain has been found to cross-link to preproteins, thought to indicate a role in preprotein binding. The pre-protein cross-linking domain is comprised of two sub domains that are inserted within the ATPase domain [ PUBMED:12242434 ]. collapse
GO process:	protein import (GO:0017038)
GO component:	membrane (GO:0016020)
Family alignment:	View the Family alignment or the Alignment consensus sequence
There are 24 367 SecA_PP_bind domains in 24 364 proteins in SMART's NRDB database.

Taxonomic distribution of proteins containing SecA_PP_bind domains

The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing SecA_PP_bind domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.

Predicted cellular role

Cellular role:

Relevant references for this domain

Primary literature for the SecA_PP_bind domain is listed below. Automatically-derived, secondary literature is also available.

KEGG pathways involving proteins which contain this domain

This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a SecA_PP_bind domain which could be assigned to a KEGG orthologous group, and not all proteins containing SecA_PP_bind domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.

KEGG pathways

Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

KEGG orthologous groups

Some of these KOs are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

3D structures in PDB containing this domain

Links to other resources describing this domain

Pfam	SecA_PP_bind
InterPro	IPR011130