The Pfam:RyR domain within your query sequence starts at position 2819 and ends at position 2907, and its E-value is 9.4e-34.

GYSPRAIDMSNVTLSRDLHAMAEMMAENYHNIWAKKKKLELESKGGGNHPLLVPYDTLTAKEKAKDREKAQDIFKFLQISGYVVSRGFK
Pfam:RyR

Pfam:RyR
Pfam domain

Pfam ACC: