The Pfam:USP8_dimer domain within your query sequence starts at position 19 and ends at position 112, and its E-value is 5.8e-18.

HTDVSLSPEERVRALSKLGCNISINEDITPRRYFRSGVEMERMASVYLEEGNLENAFVLYNKFITLFVEKLPSHRDYQQCAVPEKQDIMKKLKE
Pfam:USP8_dimer

Pfam:USP8_dimer
Pfam domain

Pfam ACC: